What the Heck are Exosomes?

WEBVTT

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[SPEAKER_01]: if you're going to spend a lot of money on something like I'm a big soda drinker, I cannot drink Dr. Thunder y'all like it.

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[SPEAKER_01]: I can't.

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[SPEAKER_03]: Hey guys, welcome back to a skin-based pod.

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[SPEAKER_03]: I'm your host Lina, License Estition, and today I have Georgia, Georgia Davenport, License Estition, Kristen, Kristen Sandborn, License Estition, and Kelsey!

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[SPEAKER_03]: You are back with us today.

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[SPEAKER_03]: I am.

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[SPEAKER_03]: Say your new title.

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[SPEAKER_03]: Say new last name, I know.

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[SPEAKER_03]: Oh, well, she had her new last name last time.

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[SPEAKER_01]: Oh, did she?

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[SPEAKER_03]: Yeah.

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[SPEAKER_01]: Yeah, that's okay.

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[SPEAKER_01]: It's still new, it's still fun.

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[SPEAKER_01]: So fresh, we can still bring it up.

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[SPEAKER_01]: Yeah, so Kelsey Rhodes and I am an independent aesthetic partner now and welcome to season three.

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[SPEAKER_03]: Yeah, what?

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[SPEAKER_03]: Oh, I don't know.

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[SPEAKER_03]: I don't have it.

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[SPEAKER_03]: Shelby's got it.

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[SPEAKER_03]: Season three of A-Skin Babes today since Miss Kelsey is with Mrs.

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[SPEAKER_03]: Sorry.

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[UNKNOWN]: Yeah.

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[SPEAKER_03]: Okay, now that's funny, the last episode, I pronounced my mom's name wrong.

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[SPEAKER_03]: Did anyone catch that?

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[SPEAKER_00]: No.

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[SPEAKER_03]: How'd you say it?

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[SPEAKER_03]: I don't remember, but I heard it on, when we had it on the TV at the shop.

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[SPEAKER_03]: And I heard me say, I said, did I just pronounce my mom's name wrong?

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[SPEAKER_03]: I did.

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[SPEAKER_03]: Was that the same episode that you forgot my name?

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[SPEAKER_03]: No.

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[SPEAKER_03]: We've been over that.

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[SPEAKER_03]: I did not forget your name.

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[SPEAKER_03]: I forgot your last name.

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[SPEAKER_03]: Anyway, Kelsey's with a new company!

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[SPEAKER_03]: I am.

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[SPEAKER_01]: You and Tels with this new company is?

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[SPEAKER_01]: Yeah, so it's a company called Excellence Exismes.

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[SPEAKER_01]: Their age zero, and it is a brand new company to the industry.

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[SPEAKER_01]: It's very exciting.

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[SPEAKER_01]: And what are exosomes?

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[SPEAKER_01]: So, exosomes are...

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[SPEAKER_01]: extra cellular vesicles that actually produce messages between each other.

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[SPEAKER_01]: So think of it kind of like a text message or we'll take it all the way back to like high school and you're like passing notes between each other and you're kind of like hiding it from the teacher.

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[SPEAKER_01]: That's essentially what exosomes do in our body.

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[SPEAKER_03]: I went to go back to when you said day zero, because when she came two weeks ago, yep, to shop to talk about these.

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[SPEAKER_03]: And that was really interesting to me is what is day zero?

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[SPEAKER_03]: And what was that go with exesomes?

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[SPEAKER_01]: Yeah, so there's a lot of different types of exesomes out there.

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[SPEAKER_01]: There can be plant-derived exesomes, there's human exesomes, and so what makes excellent so different is their day zero.

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[SPEAKER_01]: They're actually sourced from the umbilical cord.

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[SPEAKER_01]: which makes them the most bio-available to the body because they're essentially the freshest.

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[SPEAKER_01]: And so with that, they, you know, haven't endured any aging per se.

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[SPEAKER_01]: Why would we want to use exosomes?

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[SPEAKER_01]: Yeah, so exesomes are gonna help with, like, cell repair, right, and helping with inflammation.

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[SPEAKER_01]: They're gonna help with collagen stimulation.

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[SPEAKER_01]: So as we get older, our body just doesn't function the same way that it used to.

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[SPEAKER_01]: And so we actually do have exesomes already in our body.

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[SPEAKER_01]: But as we start to age and go through life, they just kind of start to dull out essentially.

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[SPEAKER_01]: And so adding exesomes in post treatments gonna help our body function in a more youthful way

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[SPEAKER_01]: faster.

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[SPEAKER_02]: Not that I know how to use social media a lot, but whenever I'm kind of going through TikTok every now and then, I mean, it's starting to be a real big buzz with exesomes I know that several years ago is PRP, so what's kind of the difference between those two?

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[SPEAKER_01]: Yeah, so there's a lot of different ones, so I feel like growth factors is something that, you know, has been in the industry for a really long time.

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[SPEAKER_01]: our exosomes actually have growth factors in them, your body naturally has growth factors in them, and so that's something that helps with cellular repair, and so that's where as we have kind of gone through the years and the science, you know, different technologies have started to come out and things like that, exosomes have started to become, you know, like you said, a buzzword,

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[SPEAKER_01]: And so where PRP is good and it used to kind of have a place and it still does in the industry, your PRP's from yourself.

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[SPEAKER_01]: So what happens is you'll have blood drawn in the treatment room.

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[SPEAKER_01]: It's spun and it's like liquid gold and it's put back onto your skin to help your body repair itself.

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[SPEAKER_01]: But your PRP's only as healthy and as good as the human.

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[SPEAKER_02]: Yeah, and I think some of the PRP, when you heard about the vampire facials,

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[SPEAKER_02]: That's what that was.

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[SPEAKER_02]: They were taking and pulling this from your own blood and then they put the blood on your face and they'd micronyl it in.

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[SPEAKER_02]: And so that's how they were getting those that type of PRP.

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[SPEAKER_02]: And so just kind of put that in context when you were hearing about the vampire facial.

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[SPEAKER_02]: That's what we're talking about.

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[SPEAKER_01]: Yeah, absolutely.

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[SPEAKER_01]: And you.

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[SPEAKER_01]: PRP still a really good option.

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[SPEAKER_01]: There's just better options out there now because if you take PRP from somebody that's 20 per say, it's gonna be better PRP than somebody that's 50 and maybe, you know, hasn't always ate the healthiest, doesn't drink enough water, just has gone through that aging process.

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[SPEAKER_02]: I'm so sorry.

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[SPEAKER_01]: We like young exosomes on it.

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[SPEAKER_01]: It's not bold.

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[SPEAKER_01]: Yes.

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[SPEAKER_01]: Yeah, absolutely.

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[SPEAKER_01]: And that's something that, you know, post procedure.

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[SPEAKER_01]: I feel like is a lot of the times where exosomes are used, one to help with cellular repair, but it also kind of helps open up those channels to allow those exosomes to penetrate at a deeper level.

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[SPEAKER_03]: So we have exosomes as an add-on.

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[SPEAKER_03]: If you were talking to a client, what would be the benefit of adding?

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[SPEAKER_03]: Like, why would you be like, we need to add this to a facial?

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[SPEAKER_01]: aging, right?

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[SPEAKER_01]: And so there's a lot of times where we use at home skin care to help, you know, increase collagen, decrease inflammation, and you know, truly naturally age.

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[SPEAKER_01]: I think that that's really a key word and why you're seeing exosomes really pop up in the industry is

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[SPEAKER_01]: people want that regenerative medicine.

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[SPEAKER_01]: And that's something that's really becoming huge in the aesthetic space.

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[SPEAKER_01]: And exesomes are going to help with that.

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[SPEAKER_01]: So they're actually going to help your body function in a more normal way.

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[SPEAKER_01]: So yes, we're adding exesomes, but they're actually triggering your body to start functioning more youthfully.

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[SPEAKER_01]: So college and stimulation.

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[SPEAKER_01]: They do help with the downtime with procedures as well because they're going to help reduce that inflammation.

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[SPEAKER_00]: I had a client that added on exosomes and we did micronatal ink and her redness was gone and like half the amount of time that typically would actually cause a badting next to their own.

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[SPEAKER_02]: And that's a professional tell me a analogy because I'm always into analogies is with exosomes think about doing a like a micronatal treatment and compare that to like a car accident.

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[SPEAKER_02]: And somebody running in with the first day kit versus lifelike ambulances.

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[SPEAKER_02]: and then, you know, fire trucks showing up at the accident.

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[SPEAKER_02]: And so that's kind of your, you're looking at increased healing, you know, a quick recovery time, and by doing that, you know, your skin's going to bounce back faster.

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[SPEAKER_01]: Yeah.

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[SPEAKER_01]: Absolutely.

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[SPEAKER_01]: And that's, you know, just like what you said, we want inflammation, inflammation is good.

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[SPEAKER_01]: It's why we're creating those micro injuries when we are doing micro-needling RF micro-needling lasers, things like that.

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[SPEAKER_01]: But from a downtime standpoint,

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[SPEAKER_01]: somebody that's 10 years old versus somebody that's 50, 60, 70, let's say they both take the same fall, scrape their knees.

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[SPEAKER_01]: The 10 year old's going to heal so much faster than somebody that's older because their body is just functioning faster to help repair itself.

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[SPEAKER_01]: And so as we add exosomes on, it's just going to help especially people that are 30 pluses our aging starts to decline.

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[SPEAKER_01]: It's just going to help your body heal faster.

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[SPEAKER_02]: And you'll have a bit of a superpower towards those

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[SPEAKER_03]: Well, it's really cool about your company is also your exesomes could be you had a hair for the hair restoration That's right.

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[SPEAKER_01]: Oh my gosh.

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[SPEAKER_01]: Those results are so amazing.

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[SPEAKER_01]: I don't even you have a husband that need this Well, and I think that's something that also is becoming again really popular in the industry because DLPs have become so popular And people go through drastic weight loss really quickly in all of a sudden.

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[SPEAKER_01]: I mean the first thing that stops

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[SPEAKER_01]: You know, your hair stops growing.

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[SPEAKER_01]: It starts falling out because your bodies and shock.

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[SPEAKER_01]: And so being able to use exesomes for hair restoration has been huge and I've seen a lot of like after pregnancy.

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[SPEAKER_00]: Oh, like hair loss in my graveyard.

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[SPEAKER_00]: So I'm sure it could also have a ton with that.

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[SPEAKER_01]: Oh, absolutely.

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[SPEAKER_01]: Anybody that's struggling from any sort of hair loss, adding exosomes back in.

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[SPEAKER_01]: Again, it's telling those cells to function in a more youthful way.

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[SPEAKER_01]: It's telling them to stimulate collagen.

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[SPEAKER_01]: It's helping the hair follicles be a little bit healthier.

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[SPEAKER_01]: And so the best way to do that is with micro-neudling because, yes, we have our hair follicles.

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[SPEAKER_01]: And so they are going to penetrate exosomes or at a cellular level small enough to penetrate anyways.

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[SPEAKER_01]: But when we micro-neudle with them,

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[SPEAKER_02]: it is going to help them penetrate deeper and work faster and the clinicals that I showed you guys were so good and it was only nine months which is amazing yeah for those that are kind of new to micro kneeling they can micro kneeling as you're aerating the yard and you're going through and you're aerating the yard and then you're dropping in the exesomes kind of like you drop in fertilizer so that can drop down towards the roots of that grass yeah and so that's kind of an analogy

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[SPEAKER_02]: I think we had a lot of analogies with the kids growing up having kids and eight grandkids.

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[SPEAKER_02]: We do a lot of comparisons.

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[SPEAKER_03]: Yeah.

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[SPEAKER_03]: Okay.

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[SPEAKER_03]: And then there was also, because we use other exodombs too.

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[SPEAKER_03]: So what are the difference between like different exodombs?

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[SPEAKER_03]: I know like yours as your story.

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[SPEAKER_03]: Well, yeah, I forget.

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[SPEAKER_03]: There's also

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[SPEAKER_01]: yeah the way they're stored or come yeah that's I mean that's a really great question because there are so many out there you've seen them in topical products you've also see them used post procedure and so you know there are plant-derived exosomes which

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[SPEAKER_01]: again that they come from plants and so from a cellular level they don't necessarily match up a hundred percent of the way but plant exosomes are really great for reducing inflammation just not so much from a cellular repair level.

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[SPEAKER_01]: It's more of a food.

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[SPEAKER_02]: It's more of a medicine where the existence of human exosomes is more of a going in and you change these structures.

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[SPEAKER_01]: Yeah, absolutely.

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[SPEAKER_01]: And so you have them human exosomes.

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[SPEAKER_01]: You can source them anywhere from like embiblical cord to other sources in the body.

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[SPEAKER_01]: I love the question about like the freeze-dried ones because that's definitely a really hot topic right now.

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[SPEAKER_01]: Is the freeze-dried exosomes out there in wall, yes, from a stability standpoint, in a shelf life standpoint, it's great.

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[SPEAKER_01]: But when you take those exosomes and you freeze-dry them, now you are breaking up the integrity of that exosome.

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[SPEAKER_01]: And so we actually have a clinical study out there showing a freeze-dryed exosome versus a frozen exosome or a day zero.

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[SPEAKER_01]: So we don't actually decorate our exosomes and they're actually fully intact.

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[SPEAKER_01]: And so then when they go in the skin, they're able to function faster and better because you don't have a broken exosome.

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[SPEAKER_03]: No way when you're paying the $100 for that, because you're getting, oh yeah, yeah, exactly.

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[SPEAKER_01]: You're getting the best benefit from it, right?

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[SPEAKER_01]: So kind of think of it like if you're going to spend a lot of money on something like I'm a big soda drinker.

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[SPEAKER_01]: I cannot drink Dr. Thunder y'all like it.

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[SPEAKER_01]: I can't, you will never catch me.

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[SPEAKER_01]: I am a Dr. Pepper girly through and through.

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[SPEAKER_01]: And so if I'm gonna spend the money on something, yes, I might pay a little extra for Dr. Pepper, but I'm getting the best quality product out there.

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[SPEAKER_01]: And I think, you know, skin care's the same way.

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[SPEAKER_01]: Treatments are the same way.

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[SPEAKER_01]: Yes, it might cost more, but wouldn't you rather spend a little bit more money on something that's fully effective versus something that's just kind of half working.

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[SPEAKER_02]: For sure.

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[SPEAKER_02]: Well, we're excited because Mr. Erick's going to be coming back to the shop in two weeks.

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[SPEAKER_02]: And so those of you that have missed Mr. Erick, but he has kind of a bald patch on top of his head.

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[SPEAKER_02]: So, um, we so excited for Amy, a test subject to, let's see.

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[SPEAKER_00]: Oh, man, I'm trying to get calling.

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[SPEAKER_02]: And then we may have to work on Mr. Nina too.

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[SPEAKER_02]: So, yeah.

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[SPEAKER_02]: And see if we can get calling to be our test subjects for growing some new hair.

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[SPEAKER_02]: Yeah, absolutely.

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[SPEAKER_03]: And now we talked about what the benefits of exosomes are, but like what kind of results

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[SPEAKER_03]: the results.

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[SPEAKER_01]: I think it's going to depend on the patient's concerns, right?

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[SPEAKER_01]: So with hair specifically, our clinicals, we saw, you know, after one migraine-ealing session with exosomes applied, roughly about nine months, hair grows a little bit slower.

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[SPEAKER_01]: I mean, I think within like the first few weeks, potentially, especially women, maybe start noticing.

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[SPEAKER_01]: some more baby hairs and growth that way versus that long term it's going to start growing out men maybe a little bit faster because typically most of them have shorter hair and then as far as like fine lines wringles same thing usually within I'd say six to eight weeks they'll kind of start noticing it and just like anything we do a series of treatments is going to be the best so if you have somebody with just some superficial fine lines wringles maybe somebody in their 30s

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[SPEAKER_01]: One treatment might be great for them to help with their skin concerns, but if you have some of it's a little bit older, maybe has those deeper fine lines wrinkles really is focusing on that college in production.

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[SPEAKER_01]: A series of three to four is going to be best.

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[SPEAKER_01]: Okay.

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[SPEAKER_03]: Is anyone else having any questions about ex-isdom?

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[SPEAKER_02]: I think there's just a cool.

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[SPEAKER_02]: I've been excited about the ex-isdoms.

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[SPEAKER_02]: We've been using them, and so I think that this new product is going to be a lot of fun.

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[SPEAKER_02]: And we're definitely going to get to be invited and get her a chance that she can start working with some advice.

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[SPEAKER_03]: I wish you have a lot of advice.

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[SPEAKER_02]: Oh, yeah.

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[SPEAKER_03]: I'm going to ask you if you can bring.

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[SPEAKER_03]: I almost did, oh my gosh, you should have told my parents, because I thought that was so cool.

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[SPEAKER_01]: Yeah, so I should have told me, I'd say sorry, I think in my car, which is in the parking garage.

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[SPEAKER_01]: So there is a device that

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[SPEAKER_01]: you can use also that creates zero downtime.

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[SPEAKER_01]: It's an ultrasonic device.

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[SPEAKER_01]: And what's super cool about that is for the patients that maybe don't want micro-needling or you're using exosomes in a facial or like we were talking about with hair.

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[SPEAKER_01]: Micro-needling in hair is...

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[SPEAKER_01]: Hopefully I, okay, I was going to say it.

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[SPEAKER_01]: It is not always the most comfortable.

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[SPEAKER_01]: You get amazing results from it.

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[SPEAKER_01]: And so this ultrasonic device actually allows us to penetrate those exosomes down at a deeper level at that dermal level to start working faster with how actually disrupting the skin like micro-needling does.

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[SPEAKER_01]: And so how it works is you put it across the skin.

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[SPEAKER_01]: It creates a sonic vibration which disrupts the skin for about 10 to 15 minutes.

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[SPEAKER_01]: It allows us to penetrate those exosome, so those exosomes come out of the device as it is going across the skin or across the hair just helps them work a little bit faster and then it also has a red light and blue light that you guys can use while you're using it and so if a patient has concerns with fine lights and wrinkles, we can put the red light on and get a little bit of red light therapy or if it's blemishes, breakouts, things like that, the blue light's amazing for that as well.

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[SPEAKER_02]: Now, can it be used on top of micro-needling?

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[SPEAKER_01]: Yes, actually now.

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[SPEAKER_01]: So we have two different tips that come with it.

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[SPEAKER_01]: One of them is a little bit more exfoliating.

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[SPEAKER_01]: And I wouldn't say exfoliating is far as like a derma- Like a micro-dermab region.

15:17.238 --> 15:38.436
[SPEAKER_01]: type of exfoliating, but there is a smooth tip now, and so you absolutely could do it on top of micro-needling as well, and there's a clinical study with it where micro-needling again, we're kind of puncturing the skin, and so the exosomes are really only getting into those small channels, where if we're using the Juvisonic, you get a little bit deeper, more even penetration using it.

15:38.416 --> 15:42.945
[SPEAKER_02]: Well, I know that there's already a purchase week quest across to Mr. Erick's desk.

15:42.985 --> 15:46.331
[SPEAKER_02]: So, hopefully we will have this device before long.

15:46.832 --> 15:56.290
[SPEAKER_02]: Yeah, and be able to incorporate that into some of our treatments, especially our marketing lane treatments, because we're doing a lot more of the

15:56.270 --> 16:03.841
[SPEAKER_02]: I know right now, is that time of the year where I'm doing quite a few of the nanofracture macronoline or F treatments.

16:03.861 --> 16:06.265
[SPEAKER_02]: And so can that be used on top of that too?

16:06.946 --> 16:11.392
[SPEAKER_01]: Yes and no, I think a lot of it's going to pin on how deep you guys are going, and how aggressive you guys are going.

16:11.793 --> 16:14.317
[SPEAKER_01]: But you could definitely use it as a standalone product as well.

16:14.357 --> 16:17.542
[SPEAKER_01]: Which is really nice because now we can incorporate exosome facials.

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[SPEAKER_01]: Yes.

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[SPEAKER_01]: With it versus the patients having to commit to that downtime from micro-needling.

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[UNKNOWN]: Okay.

16:23.590 --> 16:26.133
[SPEAKER_02]: Yeah, we look forward to maybe add that soon.

16:26.853 --> 16:32.920
[SPEAKER_02]: Yeah, and, you know, if you guys are in the office, you might hit Mr. Eric up and ask him if he's purchased that new product for us yet.

16:33.460 --> 16:33.941
[SPEAKER_03]: I like it.

16:34.802 --> 16:37.305
[SPEAKER_03]: I was kind of stuck on it when Kelsey came and talked.

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[SPEAKER_01]: I know.

16:37.845 --> 16:38.125
[SPEAKER_01]: I know.

16:38.626 --> 16:41.329
[SPEAKER_01]: Yeah, I love that there's zero downtime with it.

16:41.529 --> 16:43.511
[SPEAKER_01]: I love that there's red light blue light.

16:43.611 --> 16:50.539
[SPEAKER_01]: And it kind of allows you guys another avenue to incorporate exosomes and for the fish.

16:50.559 --> 16:52.821
[SPEAKER_02]: Really penetrate where they need to penetrate.

16:52.801 --> 16:55.648
[SPEAKER_02]: Yeah, I think that's the whole purpose is to achieve results.

16:56.169 --> 16:56.269
[SPEAKER_01]: Yeah.

16:56.289 --> 17:05.230
[SPEAKER_02]: I mean, we do have some clients that come in and they want that European facial that relaxing feeling, but 95% of our clients are coming in to correct problems.

17:05.551 --> 17:06.473
[SPEAKER_02]: So that's why we are.

17:06.689 --> 17:13.978
[SPEAKER_02]: really seeking the technology and the knowledge and everything to try to get those results for them.

17:14.278 --> 17:14.619
[SPEAKER_01]: Yeah.

17:14.639 --> 17:17.983
[SPEAKER_01]: And the nice part about micro needling is you can do it all year round, right?

17:18.003 --> 17:20.286
[SPEAKER_01]: Where we can't necessarily do lasers all year round.

17:20.306 --> 17:22.569
[SPEAKER_01]: And so this is also something that you can add on.

17:22.589 --> 17:26.073
[SPEAKER_01]: It doesn't matter the time of year to add exosomes into micro needling.

17:27.335 --> 17:28.036
[SPEAKER_03]: I love it.

17:28.056 --> 17:28.717
[SPEAKER_03]: All right.

17:28.797 --> 17:30.899
[SPEAKER_03]: Well, I think that's all the time we have for today.

17:30.939 --> 17:33.102
[SPEAKER_03]: Let's say one else has any last questions for Kelsey.

17:33.352 --> 17:34.053
[SPEAKER_00]: I don't think so.

17:34.634 --> 17:35.235
[SPEAKER_02]: I think she's back.

17:35.355 --> 17:36.036
[SPEAKER_02]: I think we will.

17:36.257 --> 17:40.724
[SPEAKER_02]: We'll set up a time to come and see us and we're going to be working on those exesomes facials.

17:41.125 --> 17:41.986
[SPEAKER_03]: Yeah, absolutely.

17:42.006 --> 17:43.028
[SPEAKER_03]: Look at those ready for you guys.

17:43.408 --> 17:45.312
[SPEAKER_03]: Well, thank you guys for hanging out with me today.

17:45.352 --> 17:47.034
[SPEAKER_03]: Thank you, Kelsey, for hanging out with us.

17:47.215 --> 17:48.797
[SPEAKER_03]: And we will see you guys next week.

17:48.917 --> 17:49.979
[SPEAKER_03]: Bye, guys.

17:50.420 --> 17:50.500
[UNKNOWN]: Bye.